✅Overview:
Duhuo Jisheng Tang is a classical TCM formula traditionally used to dispel wind and dampness, alleviate pain, and nourish the liver and kidneys. It is commonly prescribed for conditions characterized by chronic pain and weakness in the lower back and knees, often associated with wind-dampness obstruction and liver-kidney deficiency.
✅Composition:
The formula consists of multiple herbs, with Pubescent Angelica Root (Du Huo) serving as the principal ingredient. Other components include Mulberry Mistletoe (Sang Ji Sheng), Eucommia Bark (Du Zhong), Achyranthes Root (Niu Xi), Gentian Root (Qin Jiao), Poria (Fu Ling), Cinnamon Bark (Rou Gui), Saposhnikovia Root (Fang Feng), Szechuan Lovage Rhizome (Chuan Xiong), Chinese Angelica Root (Dang Gui), White Peony Root (Bai Shao), Rehmannia Root (Shu Di Huang), Codonopsis Root (Dang Shen), and Licorice Root (Gan Cao).
✅Scientific Evidence:
A systematic review published in BMJ Open examined the efficacy of Duhuo Jisheng Tang in managing knee osteoarthritis. The review included 12 randomized clinical trials with a total of 982 participants. The findings suggested that Duhuo Jisheng Tang, when combined with conventional treatments such as glucosamine or meloxicam, significantly improved functional activities and reduced pain in individuals with KOA. However, the studies reviewed were noted to have a high risk of bias and methodological limitations, indicating the need for more rigorous research to confirm these results.
✅Conclusion:
While Duhuo Jisheng Tang shows promise as a complementary treatment for knee osteoarthritis, current scientific evidence is limited and of variable quality. Further well-designed clinical trials are necessary to establish its efficacy and safety definitively. Individuals considering this herbal formula should consult with a qualified healthcare professional to ensure it is appropriate for their specific condition and to discuss potential interactions with other treatments
✅Reference:
Zhang W, Wang S, Zhang R, Zhang Y, Li X, Lin Y, Wei X. Evidence of Chinese herbal medicine Duhuo Jisheng decoction for knee osteoarthritis: a systematic review of randomised clinical trials. BMJ Open. 2016 Jan 4;6(1):e008973. doi: 10.1136/bmjopen-2015-008973. Erratum in: BMJ Open. 2016 Jan 19;6(1):e008973corr1. doi: 10.1136/bmjopen-2015-008973corr1. PMID: 26729379; PMCID: PMC4716222.